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Because clinical studies are conducted under widely varying conditionsadverse reaction rates observed in the clinical studies of a drug cannot be directly compared to rates in the clinical studies of another drug and may not reflect the rates observed in clinical practice.

CRESTORrosuvastatin calciumis a synthetic lipid-lowering agent for oral administration.

CRESTOR significantly increased INR in patients receiving coumarin anticoagulantsThereforecaution should be exercised when coumarin anticoagulants are given in conjunction with CRESTORIn patients taking coumarin anticoagulants and CRESTOR concomitantlyINR should be determined before starting CRESTOR and frequently enough during early therapy to ensure that no significant alteration of INR occurssee WARNINGS AND PRECAUTIONS and CLINICAL PHARMACOLOGY

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however, if you are having side effects from statins, you can generally get by with a very low dose, like crestor 2.

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