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Renal function should be regularly monitored during treatment with losartan as it may deteriorateThis applies particularly when losartan is given in the presence of other conditionsfeverdehydrationlikely to impair renal function.

COZAARlosartan potassiumis an angiotensin II receptor blocker acting on the AT 1 receptor subtypeLosartan potassiuma non-peptide moleculeis chemically described as 2-butyl-4-chloro-1po-1Htetrazol5-ylphenyl)benzyl]imidazole-5-methanol monopotassium salt.

Before having surgerytell your doctor or dentist about all the products you useincluding prescription drugsnonprescription drugsand herbal products

Numerous antihypertensive drugsfrom a variety of pharmacologic classes and with different mechanisms of actionhave been shown in randomized controlled trials to reduce cardiovascular morbidity and mortalityand it can be concluded that it is blood pressure reductionand not some other pharmacologic property of the drugsthat is largely responsible for those benefitsThe largest and most consistent cardiovascular outcome benefit has been a reduction in the risk of strokebut reductions in myocardial infarction and cardiovascular mortality also have been seen regularly.

Although losartan may be used to prevent kidney problems or treat people who have kidney problemsit may also rarely cause serious kidney problems or make them worseYour doctor will check your kidney function while you are taking losartanTell your doctor right away if you have any signs of kidney problems such as a change in the amount of urine.

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