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In patients with chronic renal impairmentwhose creatinine clearance ranged from 9-55 ml/minthe disposition of a single dose of 14 C-finasteride was not different from that in healthy volunteersProtein binding also did not differ in patients with renal impairmentA portion of the metabolites which normally is excreted renally was excreted in the faecesIt therefore appears that faecal excretion increases commensurate to the decrease in urinary excretion of metabolitesDosage adjustment in non-dialysed patients with renal impairment is not necessary.
Physicians should inform patients that women who are pregnant or may potentially be pregnant should not handle crushed or broken PROSCAR tablets because of the possibility of absorption of finasteride and the subsequent potential risk to the male fetusPROSCAR tablets are coated and will prevent contact with the active ingredient during normal handlingprovided that the tablets have not been broken or crushedIf a woman who is pregnant or may potentially be pregnant comes in contact with crushed or broken PROSCAR tabletsthe contact area should be washed immediately with soap and watersee CONTRAINDICATIONSWARNINGS AND PRECAUTIONSUse In Specific PopulationsHOW SUPPLIED/Storage And Handling
Using Proscar may increase your risk of developing prostate cancerYour doctor will perform tests to make sure you do not have other conditions that would prevent you from safely using Proscar.
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finasteride proscar is used alone or in combination with another medication doxazosin cardura to treat benign prostatic hypertrophy bph, enlargement of the prostate gland .
