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One month of therapy with leflunomide costs 375 compared with 15 to 31 for sulfasalazine and 36 to 47 for methotrexate figures based on average wholesale prices in red book.
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The good newsThese side effects can often be short-circuited by taking a folic acid supplementFolic acid is the synthetic form of folateOne study found that RA patients on methotrexate who took folic acid supplements lowered the risk of GI problems and mouth sores by 79 percent.
This medication may make you more sensitive to the sunLimit your time in the sunAvoid tanning booths and sunlampsUse sunscreen and wear protective clothing when outdoorsTell your doctor right away if you get sunburned or have skin blisters/redness.
Methotrexate should NOT be taken if you are pregnant or planning to get pregnant or breast-feedingMethotrexate may be temporarily discontinued if you are having surgeryincluding dental surgeryInform your surgeon or dentist about the medication prior to the surgeryMethotrexate sensitises your skin to sunlightAvoid unnecessary or prolonged sun exposure and wear protective gearIf you have psoriasisyour sores may worsen if you expose your skin to sunlight while you are taking methotrexateVaccinationsespecially live onesare not to be given while you are taking methotrexateDiscuss this with your doctor for safer options.
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teniposide moderate use methotrexate and teniposide together with caution; increased methotrexate levels and increased methotrexate toxicity may occur.
