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Ceftizoxime moderate nephrotoxicity associated with cephalosporins may be potentiated by concomitant furosemide therapy.
Information about Furosemide.
Overdose and treatment Signs and symptoms of overdose include profound electrolyte and volume depletionwhich may precipitate circulatory collapseTreatment is chiefly supportivereplace fluids and electrolytes.
Adverse reactions CNSvertigoheadachedizzinessparesthesiarestlessnessfeverCVvolume depletion and dehydrationorthostatic hypotensionthrombophlebitis with I.VadministrationEENTtransient deafness with too-rapid I.Vinjectionblurred visionGIabdominal discomfort and paindiarrheaanorexianauseavomitingconstipationPANCREATITISGUnocturiaazotemiapolyuriafrequent urinationrenal failureoliguriaHematologicagranulocytosisleukopeniathrombocytopeniaanemiaaplastic anemiaMetabolichypokalemiahypochloremic alkalosisasymptomatic hyperuricemiafluid and electrolyte imbalancesincluding dilutional hyponatremiahypocalcemiahypomagnesemiahyperglycemiaimpaired glucose toleranceMusculoskeletalmuscle spasmweaknessSkindermatitispurpuratransient pain at I.Minjection site.
References are publications that support the biological activity of the product.
Overdose and treatment Signs and symptoms of overdose include profound electrolyte and volume depletionwhich may precipitate circulatory collapseTreatment is chiefly supportivereplace fluids and electrolytes.
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the patient was also given smz tmp 400 80 mg day and furosemide 160 mg day .
