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Concomitant treatment with clozaril and cyp2d6 or cyp3a4 inhibitors e.
Information about Clozaril.
This medication may rarely make your blood sugar risewhich can cause or worsen diabetesTell your doctor right away if you have symptoms of high blood sugar such as increased thirst/urinationIf you already have diabetescheck your blood sugar regularly as directed and share the results with your doctorYour doctor may need to adjust your diabetes medicationexercise programor diet.
This medication may pass into breast milk and have undesirable effects on a nursing infantBreast feeding is not recommended while taking clozapineConsult your doctor before breast-feeding.
For patients to receive this medicationall doctorspharmacistsand patients must agree tounderstandand carefully follow the requirements of the Clozapine REMS ProgramThese requirements apply in the United StatesIf you live in Canada or any other countryconsult your doctor and pharmacist for your country’s regulations.
Take Clozaril exactly as prescribed by your doctorFollow all directions on your prescription labelYour doctor may occasionally change your doseDo not take this medicine in larger or smaller amounts or for longer than recommended.
Do not stop taking clozapine without consulting your doctorSome conditions may become worse when the drug is suddenly stoppedAlsoyou may experience symptoms such as severe sweatingheadachenauseavomitingand diarrheaTo prevent these symptoms while you are stopping treatment with this drugyour doctor may reduce your dose graduallyConsult your doctor or pharmacist for more detailsReport any new or worsening symptoms right away.
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this evidence, consistent with the view that clozaril is preferentially more active at limbic than at striatal dopamine receptors, may explain the relative freedom of clozaril from extrapyramidal side effects.
