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Depakote can cause liver failure that may be fatalespecially in children under age 2 and in people with liver problems caused by certain genetic disorders.
Abnormal dreams absence of or decrease in body movement anxiety bloody nose blurred vision bruising burningcrawlingitchingnumbnesspricklingpins and needlesor tingling feelings change in personality change in walking and balance changes in patterns and rhythms of speech chest pain chills cloudy urine clumsiness or unsteadiness cold sweats constipation darkened urine degenerative disease of the joint difficulty with moving dizziness dizzinessfaintnessor lightheadedness when getting up from a lying or sitting position suddenly dry mouth excessive muscle tone fastirregularpoundingor racing heartbeat or pulse feeling of warmth or heat flushing or redness of the skinespecially on the face and neck frequent urge to urinate heavy non-menstrual vaginal bleeding hyperventilation increased need to urinate indigestion lack of coordination largeflatblue or purplish patches in the skin leg cramps lip smacking or puckering loss of bladder control loss of strength or energy multiple swollen and inflamed skin lesions muscle pain or stiffness muscle tension or tightness normal menstrual bleeding occurring earlierpossibly lasting longer than expected pains in the stomachsideor abdomenpossibly radiating to the back passing urine more often pounding in the ears puffing of the cheeks rapid or worm-like movements of the tongue rapid weight gain restlessness seeinghearingor feeling things that are not there shakiness and unsteady walk slurred speech small red or purple spots on the skin sweating swollen joints trouble with speaking twitching uncontrolled chewing movements uncontrolled movements of the arms and legs unsteadinesstremblingor other problems with muscle control or coordination vomiting of blood or material that looks like coffee grounds yellow eyes or skin.
Frequency not reportedAplastic anemiabone marrow suppressionbruisingeosinophiliafrank hemorrhagehypofibrinogenemiaanemia including macrocytic with or without folate deficiencyrelative lymphocytosisRef]
Are there any disadvantages to DepakoteThe biggest disadvantages of Depakote are potential side effects which include possible liver damage or pancreatitisPregnant women are also typically advised not to take the medication due to the risk of birth defects.
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