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Very rarelyfatalities have been reported due to angioedema associated with laryngeal oedema or tongue oedemaPatients with involvement of the tongueglottis or larynxare likely to experience airway obstructionespecially those with a history of airway surgeryIn such cases emergency therapy should be administered promptlyThis may include the administration of adrenaline and/or the maintenance of a patent airwayThe patient should be under close medical supervision until complete and sustained resolution of symptoms has occurred.
In some patients with heart failure who have normal or low blood pressureadditional lowering of systemic blood pressure may occur with lisinoprilThis effect is anticipated and is not usually a reason to discontinue treatmentIf hypotension becomes symptomatica reduction of dose or discontinuation of lisinopril-hydrochlorothiazide may be necessary.
Potassium supplementspotassium-sparing diuretics or potassium-containing salt substitutes and other medicinal products that may increase serum potassium levels.
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however, there they come in a combination pill zestoretic lisinopril hctz that is more affordable, and more convenient, than taking two separate medications.