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Although plasma protein binding and absolute bioavailability of metaxalone are not knownthe apparent volume of distributionV/F.
It is unknown if this drug passes into breast milkConsult your doctor before breast-feeding.
Metaxalone has no direct action on the contractile mechanism of striated musclethe motor end plateor the nerve fiber.
This medication may increase serotonin and rarely cause a very serious condition called serotonin syndrome/toxicityThe risk increases if you are also taking other drugs that increase serotoninso tell your doctor or pharmacist of all the drugs you takesee Drug Interactions sectionGet medical help right away if you develop some of the following symptomsfast heartbeathallucinationsloss of coordinationsevere dizzinesssevere nausea/vomiting/diarrheatwitching musclesunexplained feverunusual agitation/restlessness.
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however, how exactly the drug skelaxin works, is not known; it does not directly act on the motor plate, striated muscle or the nerve fiber.
