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Studies in rodents and primates have shown that bupropion exhibits some pharmacologic actions common to psychostimulantsIn rodentsit has been shown to increase locomotor activityelicit a mild stereotyped behavioral responseand increase rates of responding in several schedule-controlled behavior paradigmsIn primate models to assess the positive reinforcing effects of psychoactive drugsbupropion was self-administered intravenouslyIn ratsbupropion produced amphetamine-like and cocaine-like discriminative stimulus effects in drug discrimination paradigms used to characterize the subjective effects of psychoactive drugs.
Drinking alcohol with bupropion may increase your risk of seizuresIf you drink alcohol regularlytalk with your doctor before changing the amount you drinkBupropion can also cause seizures in people who drink a lot of alcohol and then suddenly quit drinking when they start using the medication.
Accurate estimates of the incidence of adverse events associated with the use of any drug are difficult to obtainEstimates are influenced by drug dosedetection techniquesettingphysician judgmentsetcThe figures cited cannot be used to predict precisely the incidence of untoward events in the course of usual medical practice where patient characteristics and other factors differ from those that prevailed in the clinical trialsThese incidence figures also cannot be compared with those obtained from other clinical studies involving related drug products as each group of drug trials is conducted under a different set of conditions.
Report any new or worsening symptoms to your doctorsuch asmood or behavior changesanxietydepressionpanic attackstrouble sleepingor if you feel impulsiveirritableagitatedhostileaggressiverestlesshyperactivementally or physicallyor have thoughts about suicide or hurting yourself.
You may have nicotine withdrawal symptoms when you stop smokingincludingincreased appetiteweight gaintrouble sleepingtrouble concentratingslower heart ratehaving the urge to smokeand feeling anxiousrestlessdepressedangryfrustratedor irritatedThese symptoms may occur with or without using medication such as Zyban.
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bupron sr contains the same ingredients as zyban, a medicine used to help stop smoking, and aplenzin, another medicine used to treat depression.
